Adjuvants

Status Brief
History/Origins:

Developmental Milestones/Developments to Date:

Current Assessment/State of the Field:

Problems/Challenges:

Proposals:

 2009

Pollack, Andrew, “In Vaccine Additive, Benefit and Doubt, NYT, D1, Sept. 22, 2009.

  1. “Are Americans obliged to use an unproven vaccine to help protect people in other countries from the flu pandemic? That is the crux of a debate over adjuvants”
  2. “Early studies suggest that adjuvants (pronounced AD-joo-vants) could allow four times as many people to be immunized against H1N1 pandemic influenza with a given amount of vaccine.”
  3. “But while Canada and some European nations will use vaccines containing adjuvants, American officials have decided against it for now.”
  4. “Officials also fear that using an adjuvant would raise public fears about vaccine safety at a time when their challenge might be about to shift from producing enough vaccine to persuading people to use it.”
  5. “…There’s a concern that people would be reluctant to get vaccinated,’ said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases.”
  6. “Officials say, one reason to use adjuvants is that they can increase a vaccines’s potency against a virus to which it is poorly matched. But the swine flu vaccine is well matched to the virus, which has not mutated.”

Vaccination, Flu, Canada, Europe, Adjuvants

2010

Low, Donald E. and McGeer, Allison., “Pandemic (H1N1) 2009: Assessing the Response.” Canadian Medical Association Journal, November 2010. http://www.docstoc.com/docs/70230222/Pandemic-%28H1N1%29-2009-assessing-the-response

  1.  “Research published by Viboud and colleagues suggests that the first waves of the 2009 pandemic may have been more severe than is widely perceived.”
  2. “…the estimate number of years of life lost was 25% greater than duing a usual influenza season.”
  3. “The vaccine could not be made quickly enough to protect Canadians from the second wave, the complexity of delivering vaccine was badly underestimated, and attempts to deliver rapid public education about vaccination with an adjuvant vaccine failed.”
  4.  “…uncertainty and limited communication about vaccine supply hampered local and provincial coordination of delivery.”
  5. “Last year’s events clearly show that our current methods of vaccine production are too slow for an adequate response to a pandemic.”

Flu, Vaccination, Pandemic, Emergency Response, Biosecurity, Public Health, Adjuvants

 

 

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2012

“China probes ‘gutter oil in medicine’ claims,” September 3, 2012

2013

“Insight: Evidence grows for narcolepsy link to GSK swine flu shot,” Janury 20, 2013

 

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