Risk

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2013

Fouchier, Ron, García-Sastre, Adolfo,  Kawaoka, Yoshihiro et al., “Transmission Studies Resumefor Avian Flu,” ”Science Express” – Letters, January 23, 2013 http://www.sciencemag.org/content/early/2013/01/22/science.1235140.full.pdf last checked January 24, 2013.

  1. ”In January 2012, influenza virus researchers from around the world announced a voluntary pause of 60 days on any research involving highly pathogenic avian influenza H5N1 viruses leading to the generation of viruses that are more transmissible in mammals. We declared a pause to this important research to provide time to explain the public-health benefits of this work, to describe the measures in place to minimize possible risks, and to enable organizations and governments around the world to review their policies (for example on biosafety, biosecurity, oversight, and communication) regarding these experiments.”
  2. ”The World Health Organization has released recommendations on laboratory biosafety for those conducting this research, and relevant authorities in several countries have reviewed the biosafety, biosecurity, and funding conditions under which further research would be conducted on the laboratory-modified H5N1 viruses. Thus, acknowledging that the aims of the voluntary moratorium have been met in some countries and are close to being met in others, we declare an end to the voluntary moratorium on avian flu transmission studies.”
  3. ”The controversy surrounding H5N1 virus transmission research has high-lighted the need for a global approach to dealing with dual-use research of concern.”
  4. ”Because H5N1 virus transmission studies are essential for pandemic preparedness and understanding the adaptation of influenza viruses to mammals, re-searchers who have approval from their governments and institutions to conduct this research safely, under appropriate biosafety and biosecurity conditions, have a public-health responsibility to resume this important work.”
  5. ”Scientists should not restart their work in countries where, as yet, no decision has been reached on the conditions for H5N1 virus transmission research. At this time, this includes the United States and U.S.-funded research conducted in other countries.”
  6. ”Scientists should never conduct this type of research without the appropriate facilities, oversight, and all necessary approvals. We consider biosafety level 3 conditions with the considerable enhancements (BSL-3+) outlined in the referenced publications as appropriate for this type of work, but recognize that some countries may require BSL-4 conditions in accordance with applicable standards (such as Canada).”
  7. ”We fully acknowledge that this research—as with any work on infectious agents—is not without risks. However, because the risk exists in nature that an H5N1 virus capable of transmission in mammals may emerge, the benefits of this work outweigh the risks.”

Scientific Self-Governance, Dual Use, Flu, Biosafety, Biosecurity, WHO, Open Science, Oversight, Public Health, Canada, Risk, BSL, Pandemic